
21-Day Holland America Line Panama Canal Cruise
Legendary Panama Canal Voyage
An extraordinary Panama Canal crossing from Vancouver. Let the sea carry you to California, Mexico, and Colombia; transit the canal then toast to your journey on RelaxAway, Half Moon Cay.
Exclusive Offer: Receive up to $150 onboard credit in select categories on select 2026 & 2027 sailings when you book by August 19, 2026*
Ship: Nieuw Amsterdam | Cruise Line: Holland America Line | Sail Date: September 27, 2026 | From/To: Vancouver to Ft. Lauderdale| Length: 21-Nights
Interior Stateroom Cat. M From
$4,159
Per person including all taxes, fees and port expenses
Ocean View Stateroom Cat. E From
$4,369
Per person including all taxes, fees and port expenses
Balcony Stateroom Cat. BF From
$4,849
Per person including all taxes, fees and port expenses
Suite, Cat. BS4 From
$21,549
Per person including all taxes, fees and port expenses
Vancouver, British Columbia:
The perfect combination of urban meets nature, Vancouver is a hub for lovers of the great outdoors. Enjoy picturesque views of the mountains while exploring the city’s local hot spots like Stanley Park, Granville Island, Gastown and more. Don’t forget to sample the best of the local culinary and cocktail scene for something truly unique.
San Francisco, California:
San Francisco is a city of dreamers, known for its iconic Golden Gate Bridge, cable cars, and colorful Victorian houses. San Fran's vibrant cultural scene, diverse neighborhoods, and scenic beauty, from the rolling hills to the bustling waterfront, make it a captivating destination for cruise passengers.
San Diego, California:
With more than 300 days of sun every year, renowned surf spots like Del Mar and La Jolla, and a bustling culinary and craft beer scene, San Diego is a surfer's paradise and a feast for foodies. Explore distinct neighborhoods and enjoy the city’s laid-back charm on cruises to San Diego, California.
Puerto Vallarta, Mexico:
Cruise to Puerto Vallarta and find yourself immersed in dynamic culture and history. Unlike other coastal resort towns in Mexico, Puerto Vallarta ("PV" to locals), retains quite a bit of its colonial-era charm. Its town square, Plaza de Armas, and the gorgeous church of Our Lady of Guadalupe, serve as the loveliest representations of bygone ages.
Huatulco, Mexico:
Huatulco, situated on Mexico's Pacific Coast in the state of Oaxaca, has nine bays and 36 beaches, offering more than enough opportunities for fun in the sun. The most popular beach is La Entrega, with clean white sand and calm waters, perfect for snorkeling and swimming . . . or just relaxing.
Puerto Chiapas, Mexico:
For travelers arriving by cruise ship, the town of Puerto Chiapas is a jumping-off point to explore surrounding areas, including Tapachula, the second-largest city in the state of Chiapas. In addition to visiting the coffee estates and banana and cacao plantations of the area, day trips include excursions to Maya sites such as Izapa.
Puerto Quetzal, Guatemala:
Puerto Quetzal is an ideal point of departure for exploring several corners of the country. Choose your mode of transportation—plane, bus, car or boat—and decide whether you want to take in Guatemala's stunning, volcano-studded landscape, one (or more!) of the country's Maya sites, the UNESCO–recognized colonial city of Antigua (the former capital), a coffee plantation or one of the many beguiling bodies of water.
Acajulta, El Salvador:
Stunning beaches and colorful markets await on cruises to Acajutla, El Salvador. As the ship approaches, breathtaking views of the serene coastline greet your gaze. For such a small town, Acajutla has an array of things to do. Taxis offer the optimal way to travel from the port.
Panama Canal Balboa:
The town of Balboa stands at the Pacific end of one of the world's great engineering wonders, the Panama Canal. Long the administrative center of the Canal Zone, it was U.S. territory until the last day of the last century, when it was returned to Panama on December 31, 1999. The 77-kilometer (48-mile) route that begins here and ends at the Caribbean unfolds like an epic tale.
Panama Canal:
The construction of the Panama Canal is one of those epic tales from the past, an old-school feat of engineering, ambition and courage. A cruise along it today is a journey through the centuries, from the Spanish fortifications near Limón Bay to the glittering skyline of Panama City, not to mention the canal itself. Over the course of a decade a little more than a century ago, tens of thousands of workers drilled dynamite holes, drove belching steam shovels and labored with pickaxes, all the while fighting off malaria. While the French builders of the Suez Canal ultimately gave up in Panama, American crews persevered and created a route allowing ships to travel across a continent. As David McCullough recounts in his sweeping history The Path Between the Seas, it was a combination of sheer human might and engineering prowess. In 2016 an expansion more than doubled the canal's capacity, ensuring it will continue to be central to the world's maritime traffic.While many think of the Panama Canal only as a remarkable manmade achievement, the area is also of interest to naturalists. Panama’s rain forest suffered great biodiversity loss during the canal's construction, but today more than 100 species each of mammals and reptiles, as well as some 500 different birds, thrive in the nature reserves along the length of the canal.
Half Moon Cay, Bahamas:
RelaxAway, Half Moon Cay™ is Holland America Line’s award-winning private island, a Bahamian paradise reserved for our guests. Designed to inspire effortless relaxation, this idyllic retreat includes a Beach Club, serene lounging spaces, island-only menu items, and much more. Unwind in a private cabana, kayak through its crystalline lagoon, or ride horseback along the surf. Whether seeking a tranquil escape or water activities, this secluded haven delivers the ultimate private island experience.
21 Nights | Panama Canal | Holland America: Nieuw Amsterdam
- Day 1:Vancouver, B.C., CA
Sun Sep 27, 2026 | Depart 04:00 PM
- Day 2:Day At Sea
Mon Sep 28, 2026
- Day 3:Day At Sea
Tue Sep 29, 2026
- Day 4:San Francisco, California, US
Wed Sep 30, 2026 | 07:00 AM To 09:00 PM
- Day 5:Day At Sea
Thu Oct 1, 2026
- Day 6:San Diego, California, US
Fri Oct 2, 2026 | 07:00 AM To 04:00 PM
- Day 7:Day At Sea
Sat Oct 3, 2026
- Day 8:Day At Sea
Sun Oct 4, 2026
- Day 9:Puerto Vallarta, Mexico
Mon Oct 5, 2026 | 08:00 AM To 05:00 PM
- Day 10:Day At Sea
Tue Oct 6, 2026
- Day 11:Huatulco, Mexico
Wed Oct 7, 2026 | 10:00 AM To 05:00 PM
- Day 12:Puerto Chiapas, Mexico
Thu Oct 8, 2026 | 08:00 AM To 05:00 PM
- Day 13:Puerto Quetzal, Guatemala
Fri Oct 9, 2026 | 06:00 AM To 08:00 PM
- Day 14:Acajutla, El Salvador
Sat Oct 10, 2026 | 07:00 AM To 05:00 PM
- Day 15:Day At Sea
Sun Oct 11, 2026
- Day 16:Day At Sea
Mon Oct 12, 2026
- Day 17:Enter Panama Canal Balboa
Tue Oct 13, 2026 | 05:00 AM To 05:00 AM
- Day 17:Cruising Panama Canal
Tue Oct 13, 2026
- Day 17:Exit Panama Canal Cristobal
Tue Oct 13, 2026 | 07:00 PM To 07:00 PM
- Day 18:Cartagena, Colombia
Wed Oct 14, 2026 | 12:00 PM To 06:00 PM
- Day 19:Day At Sea
Thu Oct 15, 2026
- Day 20:Day At Sea
Fri Oct 16, 2026
- Day 21:RelaxAway Half Moon Cay, Bahamas- Tender
Sat Oct 17, 2026 | 08:00 AM To 02:00 PM
- Day 22:Fort Lauderdale, Florida, US
Sun Oct 18, 2026 | Arrive 07:00 AM
Nieuw Amsterdam
Signature Class ship Nieuw Amsterdam honors New York City with modern amenities, inspired design, and a robust art collection inspired by Art Deco.
- Billboard Onboard: Sing along, test your music trivia knowledge, or sit back and enjoy as chart-topping hits fill the room each night.
- World Stage: World Stage features innovative cruise ship shows and a two-story LED screen that creates a vivid wraparound display.
- Rolling Stone Lounge: Their band brings you the best in rock, pop, country and more.
- Fitness Center: Take a class in our professionally staffed Fitness Center.
- Holland America Line Navigator: Personalize your cruise experience with our free mobile-friendly tool.
- Pickleball at Sea: Enjoy complimentary lessons, tournaments, and courts with amazing top-deck views.
- Lido Market: A casual, modern marketplace, Lido Market offers the widest range of food options on board for breakfast, lunch, dinner and a late-night snack.
- Dive In: This casual poolside grill serves up the best burgers at sea, Nathan’s Famous gourmet hot dogs, golden French fries and more.
- 24-Hour Room Service: Their 24-hour room service menu offers a wide-variety of complimentary and à la carte options morning, noon and night. Enjoy breakfast on your verandah or a late night snack while watching one of our on-demand movies, all from the comfort of your stateroom.
- The Dining Room: Their flagship dining experience is a welcoming and sophisticated setting for an exquisite breakfast, lunch or superb multicourse dinner.
*Prices are in USD, per person based on double occupancy, availability and subject to change without notice. All cruises taxes, fees and port expenses are included in the pricing. All promotions are capacity controlled by Holland America Line and can be pulled at any time without notice. Above pricing is based on July 29, 2026, availability and is not guaranteed when booking. Exclusive onboard credit is based on double occupancy and cabin category (oceanview, verandah, suite) using code MVH. Other restrictions may apply. Ships’ registry: Netherlands


